Jainism teaches that "upadan" (substance or material cause) can have various types of "dosh" (defects or impurities) that affect the soul's bondage and liberation. According to Jain philosophy, particularly in the context of karma theory, there are mainly eight types of karmic impurities (ashta karma dosh) that bind the soul. These are:

1. Jnanavarniya Karma (Knowledge-obscuring)
2. Darshanavarniya Karma (Perception-obscuring)
3. Mohaniya Karma (Deluding)
4. Antaraya Karma (Obstructive)
5. Vedaniya Karma (Feeling-producing)
6. Nama Karma (Body-determining)
7. Gotra Karma (Status-determining)
8. Ayushya Karma (Life-span determining)

Each of these karmas is considered a "dosh" because it defiles the pure nature of the soul (upadan).

If you are referring specifically to the philosophical context of "upadan na dosh" (defects of substance), Jain scriptures mainly discuss the impurities that affect the soul due to karma, as described above.

If you need detailed explanations of each dosh, please let me know!